Description

Collismycin A is a specialized, high-purity antibiotic compound belonging to the pyrrolobenzodiazepine (PBD) family, identified by CAS NO 158792-24-6. This compound is valued for its potent biological activity, making it a critical intermediate and reference standard in advanced pharmaceutical research and development. It is primarily sought by research institutions and pharmaceutical companies focused on oncology, infectious disease, and novel antibiotic discovery.

Application

• Pharmaceutical Research & Development: Serves as a key reference standard and active pharmaceutical ingredient (API) intermediate in the development of novel antibiotic and anticancer therapies.
• Biochemical Research: Used as a potent tool compound in microbiological and cell-based assays to study bacterial inhibition mechanisms and cellular responses.
• Antibiotic Discovery Programs: Acts as a lead compound or a structural template for the synthesis and evaluation of new analogs with improved efficacy and safety profiles.
• Academic Research: Employed in university and institutional labs for fundamental studies on pyrrolobenzodiazepine chemistry and their interactions with DNA.
• Quality Control & Analytical Testing: Utilized as a certified reference material (CRM) in HPLC, LC-MS, and NMR for method validation and purity assessment in quality control laboratories.

Basic Information

Product Name	Collismycin A
CAS No.	158792-24-6
Molecular Formula	C22H22N2O5
Molecular Weight	394.42 g/mol
Synonyms	Collismycin A; Antibiotic MM 46115; MM 46115; (3S,3aR,10bR)-8,10-Dihydroxy-3-(hydroxymethyl)-6-methoxy-3a-methyl-1-oxo-3,3a,10,10b-tetrahydro-1H-pyrrolo[2,1-c][1,4]benzodiazepine-9-carboxylic acid; Pyrrolobenzodiazepine antibiotic
EINECS	Contact for details

Quality Control

Our Collismycin A is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards for research-grade chemicals, and specifications can be tailored to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label or COA. Keep the container in a dry, cool, and well-ventilated place. This product is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.