Description

4-Isothiocyanatobenzamide is a specialized organic compound featuring both an isothiocyanate and a benzamide functional group, making it a valuable bifunctional building block. This compound is significant for its role as a key intermediate in the synthesis of more complex molecules, particularly in pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists in the life sciences sector for creating novel active ingredients and biochemical probes.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of potential drug candidates, particularly those targeting specific enzymes or receptors.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, or plant growth regulators.
• Bioconjugation & Probe Synthesis: The reactive isothiocyanate group allows for covalent attachment to amines in proteins, peptides, or other biomolecules to create fluorescent probes or affinity labels.
• Chemical Biology Tool: Serves as a building block for activity-based probes (ABPs) used to study enzyme function and mechanism.
• Material Science Research: Potential monomer or cross-linking agent in the development of specialized polymers with unique properties.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.

Basic Information

Product Name	4-Isothiocyanatobenzamide
CAS No.	158756-25-3
Molecular Formula	C8H6N2OS
Molecular Weight	178.21 g/mol
Synonyms	p-Isothiocyanatobenzamide; 4-Carbamoylphenyl isothiocyanate; Benzamide, 4-isothiocyanato-; 1-Carbamoyl-4-isothiocyanatobenzene; Isothiocyanic acid, 4-carbamoylphenyl ester
EINECS	Contact for details

Quality Control

Our 4-Isothiocyanatobenzamide is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by FT-IR and NMR, to ensure it meets the high standards required for research and development applications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.