Description

3-Fluoro-4-Nitrobenzoyl Chloride is a high-purity, reactive aromatic acid chloride derivative. This compound serves as a critical building block in advanced organic synthesis, enabling the efficient introduction of the 3-fluoro-4-nitrobenzoyl moiety. It is primarily utilized by research and development chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries for the synthesis of active pharmaceutical ingredients (APIs), advanced intermediates, and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting specific enzyme inhibitors or receptor modulators.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides, where the fluorine and nitro groups contribute to biological activity and stability.
• Peptide Coupling Reagent: Functions as an activating agent for carboxylic acids in amide bond formation, a fundamental reaction in peptide and protein chemistry.
• Liquid Crystal & Polymer Chemistry: Employed in the synthesis of monomers and intermediates for functional polymers and liquid crystal displays (LCDs).
• Dyestuff & Pigment Intermediate: Serves as a building block for creating complex organic dyes and pigments with specific coloristic and fastness properties.
• Chemical Research & Development: Essential for academic and industrial R&D labs exploring new chemical entities, material science, and reaction methodologies.

Basic Information

Product Name	3-Fluoro-4-Nitrobenzoyl Chloride
CAS No.	157665-51-5
Molecular Formula	C7H3ClFNO3
Molecular Weight	203.56 g/mol
Synonyms	4-Nitro-3-fluorobenzoyl chloride; 3-Fluoro-4-nitrobenzoic acid chloride; Benzoic acid, 3-fluoro-4-nitro-, chloride; 3-Fluoro-4-nitrobenzoyl chloride; 3-Fluoro-4-nitro-benzoyl chloride; 157665-51-5; 4-Nitro-3-fluorobenzoic acid chloride
EINECS	Contact for details

Quality Control

Every batch of 3-Fluoro-4-Nitrobenzoyl Chloride is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the high standards required for sensitive synthetic applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles by techniques such as HPLC, GC, NMR, and IR spectroscopy is available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis. Keep away from strong bases, oxidizing agents, and sources of ignition.

Specification

Item	Specification
Appearance	White to light yellow crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.