Description

4-(2-Azidoethyl)-1,3-Dihydro-2H-Indol-2-One is a specialized heterocyclic organic compound featuring a reactive azidoethyl side chain. This unique structure makes it a valuable key intermediate and building block in advanced synthetic chemistry, particularly for the development of novel pharmaceutical agents and bioactive molecules. It is primarily needed by research institutions and pharmaceutical R&D departments focused on medicinal chemistry and drug discovery programs.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of complex drug candidates, particularly those targeting neurological and oncological pathways.
• Medicinal Chemistry Research: Used in the development and optimization of new chemical entities (NCEs) via click chemistry and other bio-conjugation techniques facilitated by the azide group.
• Bioconjugation & Probe Synthesis: The reactive azide functional group enables its use in creating fluorescent probes, affinity labels, and other tools for biochemical and cellular studies.
• Organic Synthesis: Serves as a versatile precursor for constructing more complex indole-based heterocycles and fused ring systems.
• Agrochemical Research: Potential intermediate in the development of new crop protection agents and pesticides with novel modes of action.
• Material Science: Can be utilized in the synthesis of specialty polymers and functional materials requiring specific photoactive or energetic properties.

Basic Information

Product Name	4-(2-Azidoethyl)-1,3-Dihydro-2H-Indol-2-One
CAS No.	157649-58-6
Molecular Formula	C10H10N4O
Molecular Weight	202.21 g/mol
Synonyms	2H-Indol-2-one, 1,3-dihydro-4-(2-azidoethyl)-; 4-(2-Azidoethyl)oxindole; 4-(Azidoethyl)oxindole; 4-(2-Azidoethyl)indolin-2-one; 1,3-Dihydro-4-(2-azidoethyl)-2H-indol-2-one; Azidoethyloxindole; CAS 157649-58-6
EINECS	Contact for details

Quality Control

Our 4-(2-Azidoethyl)-1,3-Dihydro-2H-Indol-2-One is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and structural identity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality parameters. Our commitment to cGMP standards ensures consistency and reliability for your research and development needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, open flames, and incompatible materials. Due to the presence of the azide functional group, appropriate safety protocols for handling energetic materials should be observed.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Typical 97-99%)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.