Description

4-Bromo-2-Nitro-1-Thiocyanatobenzene is a specialized aromatic building block characterized by its bromo, nitro, and thiocyanate functional groups. This multi-functional intermediate is critical for synthesizing complex molecules in advanced research and development. It is primarily utilized by pharmaceutical, agrochemical, and material science industries for constructing novel compounds and active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates and active pharmaceutical ingredients (APIs), particularly in medicinal chemistry research.
• Agrochemical Synthesis: Used in the development of new pesticides, herbicides, and fungicides, leveraging its reactive sites for structural diversification.
• Material Science Research: Acts as a building block for creating advanced organic materials, including liquid crystals, dyes, and functional polymers.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes and tags due to the reactivity of the thiocyanate group.
• Cross-Coupling Reactions: The bromo substituent makes it a suitable substrate for various palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) to form biaryl structures.
• Heterocyclic Chemistry: A valuable starting material for the construction of nitrogen and sulfur-containing heterocycles, which are prevalent in many bioactive molecules.

Basic Information

Product Name	4-Bromo-2-Nitro-1-Thiocyanatobenzene
CAS No.	157645-54-0
Molecular Formula	C7H3BrN2O2S
Molecular Weight	259.08 g/mol
Synonyms	1-Bromo-4-nitro-2-thiocyanatobenzene; 2-Nitro-4-bromophenyl thiocyanate; Benzene, 1-bromo-4-nitro-2-thiocyanato-; 4-Bromo-2-nitrobenzenethiocyanate; 4-Bromo-2-nitro-phenyl thiocyanate; 2-Nitro-4-bromobenzene thiocyanate; 1-Thiocyanato-4-bromo-2-nitrobenzene
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-Nitro-1-Thiocyanatobenzene is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in opaque or amber glass, or stored in dark conditions.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.