Description

2-Phenyl-2-Trifluoromethylcyclohexanone is a specialized fluorinated organic building block characterized by its unique cyclohexanone core substituted with phenyl and trifluoromethyl groups. This compound matters as a versatile intermediate for synthesizing complex molecules, where the trifluoromethyl group is prized for its ability to modulate lipophilicity, metabolic stability, and binding affinity. It is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for creating new active ingredients, as well as by manufacturers of advanced materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly for introducing the metabolically stable trifluoromethyl group.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the fluorine atoms can enhance biological activity and environmental persistence.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands or organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of fluorinated polymers or liquid crystals with specific optical or electronic properties.
• Chemical Reference Standard: Used as a high-purity standard for analytical method development and quality control in chemical production.

Basic Information

Product Name	2-Phenyl-2-Trifluoromethylcyclohexanone
CAS No.	157364-44-8
Molecular Formula	C₁₃H₁₃F₃O
Molecular Weight	242.24 g/mol
Synonyms	2-Phenyl-2-(trifluoromethyl)cyclohexan-1-one; 2-Phenyl-2-(trifluoromethyl)cyclohexanone; α-Phenyl-α-(trifluoromethyl)cyclohexanone; 1-Cyclohexyl-2,2,2-trifluoro-1-phenylethanone; 2,2,2-Trifluoro-1-cyclohexyl-1-phenylethanone; 157364-44-8; TFPC
EINECS	Contact for details

Quality Control

Our 2-Phenyl-2-Trifluoromethylcyclohexanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for advanced synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.