Description

1H-Benzimidazole-1-Acetylchloride(9Ci) is a high-purity, reactive chemical intermediate essential for advanced organic synthesis. This compound is valued for its role as a versatile acylating agent, enabling the efficient introduction of the benzimidazole-acetyl moiety into target molecules. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel benzimidazole-based drug candidates, including potential protease inhibitors and receptor antagonists.
• Agrochemical Synthesis: Used in the research and development of new fungicides and herbicides that leverage the benzimidazole scaffold for enhanced biological activity.
• Material Science Research: Serves as a precursor for creating specialized polymers and ligands with tailored electronic or binding properties.
• Bioconjugation Chemistry: Employed in the modification of biomolecules for diagnostic or therapeutic applications due to its reactive acid chloride group.
• Custom Synthesis & Contract Manufacturing: A critical reagent for fine chemical producers offering bespoke synthesis services to the life sciences industry.

Basic Information

Product Name	1H-Benzimidazole-1-Acetylchloride(9Ci)
CAS No.	157198-80-6
Molecular Formula	C9H7ClN2O
Molecular Weight	194.62 g/mol
Synonyms	1H-Benzimidazole-1-acetyl chloride; 1-Acetyl-1H-benzimidazol-1-ium chloride; 1-(Chloroacetyl)benzimidazole; 1H-Benzimidazole-1-acetic acid chloride; N-(Chloroacetyl)benzimidazole; Benzimidazol-1-ylacetyl chloride; 157198-80-6 (CAS)
EINECS	Contact for details

Quality Control

Our 1H-Benzimidazole-1-Acetylchloride(9Ci) is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and synthesis applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients' regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from strong acids and incompatible organic solvents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.