Description

3-Pyridinecarbonyl Chloride, 2-(Chlorothio)- (9Ci) is a highly reactive organosulfur compound that serves as a critical building block in advanced chemical synthesis. Its unique bifunctional structure, featuring both an acid chloride and a chlorothio group, makes it an invaluable reagent for constructing complex heterocyclic systems and introducing sulfur-containing moieties. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting neurological and oncological pathways.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides with novel modes of action.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of functionalized polymers and advanced organic electronic materials.
• Chemical Biology Probes: Facilitates the creation of activity-based probes for studying enzyme function and protein labeling.
• Custom Synthesis and Contract Manufacturing: A vital reagent for fine chemical manufacturers offering bespoke synthesis services to the life sciences sector.

Basic Information

Product Name	3-Pyridinecarbonyl Chloride, 2-(Chlorothio)- (9Ci)
CAS No.	156896-55-8
Molecular Formula	C7H3Cl2NOS
Molecular Weight	220.08 g/mol
Synonyms	2-(Chlorothio)nicotinoyl chloride; 2-Chlorosulfanylnicotinoyl chloride; 2-Pyridinecarbonyl chloride, 3-(chlorothio)-; 3-(Chlorothio)picolinoyl chloride; 2-(Chlorosulfanyl)pyridine-3-carbonyl chloride; 3-Pyridinecarbonyl chloride, 2-(chlorothio)-; 2-Chlorosulfanyl-3-pyridinecarbonyl chloride; 2-(Chlorosulfanyl)nicotinoyl chloride
EINECS	Contact for details

Quality Control

Every batch of 3-Pyridinecarbonyl Chloride, 2-(Chlorothio)- is produced and tested under strict quality management protocols to ensure consistency and reliability for your critical syntheses. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as purity, identity, and impurity profiles. Our quality systems are designed to support cGMP and ISO-guided applications, ensuring the material meets the stringent requirements of pharmaceutical and agrochemical development.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic and highly volatile nature, store under an inert atmosphere (argon or nitrogen) in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C for long-term stability. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%
Total Impurities	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.