Description

(R,S)-1-(3,4-(Methylenedioxy)-6-Nitrophenyl)Ethyl Chloroformate is a specialized chloroformate derivative used as a key chiral derivatizing agent and synthetic intermediate. This compound matters for its role in the preparation of enantiomerically pure compounds, enabling critical separation and analysis in advanced research and development. It is primarily needed by pharmaceutical R&D laboratories, analytical chemistry service providers, and fine chemical manufacturers focused on chiral synthesis and high-purity active pharmaceutical ingredient (API) development.

Application

• Chiral Derivatizing Agent (CDA) for the separation and analysis of enantiomers via HPLC, GC, or NMR.
• Synthetic Intermediate in the preparation of enantiomerically pure pharmaceuticals and agrochemicals.
• Amino Acid Analysis, facilitating the resolution of racemic amino acids for research and quality control.
• Protecting Group Chemistry for alcohols and amines in multi-step organic synthesis.
• Production of Carbamates and carbonates with specific stereochemistry.
• Reference Standard for analytical method development and validation in regulatory submissions.

Basic Information

Product Name	(R,S)-1-(3,4-(Methylenedioxy)-6-Nitrophenyl)Ethyl Chloroformate
CAS No.	156876-26-5
Molecular Formula	C10H8ClNO6
Molecular Weight	273.63 g/mol
Synonyms	1-(3,4-Methylenedioxy-6-nitrophenyl)ethyl chloroformate; 1-(6-Nitro-1,3-benzodioxol-5-yl)ethyl chloroformate; (RS)-1-(3,4-Methylenedioxy-6-nitrophenyl)ethyl chloroformate; (±)-1-(3,4-Methylenedioxy-6-nitrophenyl)ethyl chloroformate; 1-(6-Nitrobenzo[d][1,3]dioxol-5-yl)ethyl carbonochloridate; 5-(1-Chloroethoxycarbonyloxy)-6-nitro-1,3-benzodioxole; NSC 339063
EINECS	Contact for details

Quality Control

Our (R,S)-1-(3,4-(Methylenedioxy)-6-Nitrophenyl)Ethyl Chloroformate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity and chemical identity verification, to ensure it meets the stringent requirements for research and synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation. Keep away from heat, open flames, and incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	Racemic mixture (R:S ≈ 50:50)
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.