Description

Nepaprazole CAS NO 156601-79-5 is a high-purity pharmaceutical intermediate and research chemical belonging to the class of proton pump inhibitors (PPIs). It serves as a critical building block in the synthesis of advanced active pharmaceutical ingredients (APIs) targeting gastric acid-related disorders. This compound is essential for pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions engaged in developing new therapeutic agents and conducting metabolic studies.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel proton pump inhibitor drugs and related therapeutic compounds.
• Active Pharmaceutical Ingredient (API) Research: Used in research and development for creating new gastroprotective medications.
• Biochemical Research: Employed in studies investigating the mechanism of action of H+/K+ ATPase enzyme inhibition.
• Metabolite Studies: Serves as a reference standard or starting material for the synthesis and analysis of drug metabolites.
• Process Chemistry: Utilized in scale-up and optimization of synthetic routes for PPI-class pharmaceuticals.
• Analytical Standard: Functions as a high-purity standard for quality control and analytical method development (e.g., HPLC, LC-MS).

Basic Information

Product Name	Nepaprazole
CAS No.	156601-79-5
Molecular Formula	C19H21FN4O2S
Molecular Weight	388.46 g/mol
Synonyms	Nepaprazole; 2-[[(4-Fluoro-3-methoxyphenyl)methyl]sulfinyl]-1H-benzimidazole; 1H-Benzimidazole, 2-[[(4-fluoro-3-methoxyphenyl)methyl]sulfinyl]-; BY-574; BY574; Proton Pump Inhibitor Intermediate; PPI Intermediate
EINECS	Contact for details

Quality Control

Our Nepaprazole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and support current Good Manufacturing Practice (cGMP) standards for pharmaceutical intermediates. Certificates of Analysis (COA) with detailed chromatographic data (HPLC) are available for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.5% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.