Description

Motexafin Gadolinium is a paramagnetic metalloporphyrin complex, a compound of significant interest in advanced medical research and development. Its core value lies in its unique redox-active properties and its ability to act as a catalyst for oxidative stress, making it a powerful tool for targeted therapeutic applications. This product is essential for pharmaceutical R&D teams, academic researchers, and diagnostic developers working in oncology and neurology, particularly in the study of radiosensitizers and magnetic resonance imaging (MRI) contrast agents.

Application

• Pharmaceutical Research & Development: Primary application as a novel radiosensitizer in oncology to enhance the efficacy of radiation therapy against tumors.
• Diagnostic Agent Development: Investigation as a redox-active MRI contrast agent for improved imaging and detection of specific disease states.
• Neurological Disorder Studies: Research into its potential for targeting and modulating oxidative stress pathways in conditions like multiple sclerosis.
• Preclinical & Clinical Trials: Supply of high-purity material for in-vivo and in-vitro studies to evaluate therapeutic efficacy and safety profiles.
• Mechanistic Biochemistry: Used as a research chemical to study electron transfer processes and free radical chemistry in biological systems.
• Reference Standard Production: Serves as a high-quality standard for analytical method development and validation in regulatory submissions.

Basic Information

Product Name	Motexafin Gadolinium
CAS No.	156436-89-4
Molecular Formula	C52H72GdN5O14
Molecular Weight	1148.44 g/mol
Synonyms	Gadolinium Texaphyrin; Gd-Tex; Xcytrin; Motexafin Gd; Gadolinium(III) texaphyrin; PCI-0120; AN-238; Gd(III)Tex
EINECS	Contact for details

Quality Control

Our Motexafin Gadolinium is manufactured under strict quality systems to ensure the high purity and consistency required for sensitive research applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to cGMP guidelines where applicable, and our quality control protocols are designed to meet the stringent requirements of pharmaceutical development and regulatory submissions.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	Dark green to black solid
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	≤ 20 ppm
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.