Description

1-(2-Isothiocyanatoethyl)-4-[2-(3,4-Dihydro-2H-1-Benzopyran-6-Yl)-5-Oxazolyl]Pyridinium Bromide is a specialized heterocyclic organic salt featuring a reactive isothiocyanate group, making it a valuable intermediate for advanced chemical synthesis. This compound is critical for researchers and manufacturers developing novel active pharmaceutical ingredients (APIs) and high-value fine chemicals. Its primary utility lies in the pharmaceutical and life science research sectors, where it serves as a key building block for creating targeted molecular probes and therapeutic candidates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in oncology and neurological disorder research.
• Bioconjugation Reagent: Utilized for labeling proteins, antibodies, and peptides via its reactive isothiocyanate (NCS) group for diagnostic and research applications.
• Chemical Biology Probe: Serves as a building block for creating fluorescent or affinity probes to study biological pathways and protein function.
• Organic Synthesis Building Block: Used in constructing complex heterocyclic frameworks for material science and advanced organic chemistry research.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation in pharmaceutical analysis.

Basic Information

Item	Details
Product Name	1-(2-Isothiocyanatoethyl)-4-[2-(3,4-Dihydro-2H-1-Benzopyran-6-Yl)-5-Oxazolyl]Pyridinium Bromide
CAS No.	155863-02-8
Molecular Formula	C20H20BrN3O2S
Molecular Weight	446.36 g/mol
Synonyms	4-[2-(3,4-Dihydro-2H-1-benzopyran-6-yl)-1,3-oxazol-5-yl]-1-(2-isothiocyanatoethyl)pyridinium bromide; 1-(2-Isothiocyanatoethyl)-4-[2-(3,4-dihydro-2H-chromen-6-yl)-1,3-oxazol-5-yl]pyridinium bromide; Pyridinium, 1-(2-isothiocyanatoethyl)-4-[2-(3,4-dihydro-2H-1-benzopyran-6-yl)-5-oxazolyl]-, bromide; CAS 155863-02-8
EINECS	Contact for details

Quality Control

Our production of 1-(2-Isothiocyanatoethyl)-4-[2-(3,4-Dihydro-2H-1-Benzopyran-6-Yl)-5-Oxazolyl]Pyridinium Bromide adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We employ advanced analytical techniques including HPLC, NMR, and mass spectrometry to verify specifications, ensuring the material meets the exacting standards required for pharmaceutical intermediate use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.