Description

(R)-tert-Butyl 3-(Azidomethyl)Piperidine-1-Carboxylate is a high-purity chiral building block and key intermediate in advanced organic synthesis. This compound is valued for its azide functional group, which enables efficient click chemistry and other bioorthogonal transformations, facilitating the construction of complex molecular architectures. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialized fine chemicals.

Application

• Pharmaceutical Intermediate: A critical chiral synthon in the research and development of new therapeutic agents, particularly for central nervous system (CNS) targets.
• Peptide Mimetics & Conjugation: Used to introduce functional handles into peptide backbones or other biomolecules via its reactive azide group for labeling or cross-linking.
• Ligand & Catalyst Development: Serves as a precursor for synthesizing chiral ligands and organocatalysts used in asymmetric synthesis.
• Agrochemical Research: Employed in creating novel chiral compounds for crop protection and pesticide development.
• Material Science: Can be incorporated into polymers or dendrimers to introduce specific functional properties through click chemistry.
• Chemical Biology Probes: Used to create activity-based probes or affinity tags for studying biological systems.

Basic Information

Product Name	(R)-tert-Butyl 3-(Azidomethyl)Piperidine-1-Carboxylate
CAS No.	155541-67-6
Molecular Formula	C11H20N4O2
Molecular Weight	240.30 g/mol
Synonyms	1-Boc-3-(azidomethyl)-(R)-piperidine; (R)-1-(tert-Butoxycarbonyl)-3-(azidomethyl)piperidine; (R)-3-(Azidomethyl)-1-Boc-piperidine; tert-Butyl (3R)-3-(azidomethyl)piperidine-1-carboxylate; (R)-N-Boc-3-(azidomethyl)piperidine; (R)-1-N-Boc-3-azidomethylpiperidine; (R)-tert-Butyl 3-azidomethyl-1-piperidinecarboxylate; (R)-3-(Azidomethyl)piperidine-1-carboxylic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Every batch of (R)-tert-Butyl 3-(Azidomethyl)Piperidine-1-Carboxylate is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our products are characterized using advanced techniques including HPLC, GC, NMR, and IR spectroscopy. Certificates of Analysis (COA) detailing chiral purity, chemical purity, and impurity profiles are provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials. Due to the presence of an azide functional group, handle and store according to standard safety protocols for azide compounds.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.