Description

(S)-3,4-Dichloro-n-(1-(3-Isothiocyanatophenyl)-2-(1-Pyrrolidinyl)Ethyl )-n-Methylbenzeneacetamide is a specialized chiral organic compound featuring a complex molecular architecture that makes it a valuable intermediate in advanced chemical synthesis. This compound is particularly significant for its role in the research and development of novel bioactive molecules, including potential pharmaceuticals and agrochemicals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and agrochemical industries for constructing sophisticated molecular targets.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders.
• Agrochemical Research: Used as a precursor in the development of new-generation pesticides and herbicides with specific chiral activity.
• Chemical Biology Probe: Serves as a scaffold for creating isothiocyanate-containing probes used in protein labeling and target identification studies.
• Process Chemistry: Employed in route scouting and optimization for the commercial-scale production of complex active pharmaceutical ingredients (APIs).
• Academic Research: Utilized in university and institutional labs for methodological development in asymmetric synthesis and heterocyclic chemistry.
• Custom Synthesis: Foundation for contract research organizations (CROs) and CDMOs to produce bespoke compounds for client projects.

Basic Information

Product Name	(S)-3,4-Dichloro-n-(1-(3-Isothiocyanatophenyl)-2-(1-Pyrrolidinyl)Ethyl )-n-Methylbenzeneacetamide
CAS No.	155512-49-5
Molecular Formula	C22H23Cl2N3OS
Molecular Weight	464.41 g/mol
Synonyms	(S)-N-[(1R)-1-(3-Isothiocyanatophenyl)-2-(1-pyrrolidinyl)ethyl]-3,4-dichloro-N-methylbenzeneacetamide; (S)-3,4-Dichloro-N-[1-(3-isothiocyanatophenyl)-2-(pyrrolidin-1-yl)ethyl]-N-methylbenzeneacetamide; BCTC (analog related to TRPV1 antagonists); (S)-Enantiomer of a TRPV1 receptor ligand intermediate; Arylacetamide isothiocyanate derivative; Chiral pyrrolidinylethylbenzeneacetamide; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our production of (S)-3,4-Dichloro-n-(1-(3-Isothiocyanatophenyl)-2-(1-Pyrrolidinyl)Ethyl )-n-Methylbenzeneacetamide adheres to stringent quality protocols suitable for research and development applications. Each batch is characterized using advanced analytical techniques including HPLC, NMR, and MS to ensure identity, purity, and chiral integrity. Comprehensive Certificates of Analysis (COA) detailing all test results are provided to guarantee traceability and batch-to-batch consistency, supporting your critical R&D and regulatory filing needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.