Description

3-Pyridinecarbonylchloride,4-(Chloromethyl)-(9Ci) is a versatile and highly reactive bifunctional organic intermediate, crucial for constructing complex molecular architectures. Its value lies in the simultaneous presence of an acid chloride and a chloromethyl group, enabling sequential and site-specific derivatization in a single molecule. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of active pharmaceutical ingredients (APIs), advanced ligands, and functionalized heterocyclic compounds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in creating advanced herbicides, fungicides, and plant growth regulators with specific activity profiles.
• Ligand and Catalyst Development: Serves as a precursor for sophisticated chelating ligands used in catalysis and material science.
• Functional Material Research: Employed in the development of organic semiconductors, metal-organic frameworks (MOFs), and specialty polymers.
• Chemical Biology Probes: Useful for synthesizing tagged molecules and affinity probes for studying biological pathways.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom chemical synthesis services targeting complex, multi-step processes.

Basic Information

Product Name	3-Pyridinecarbonylchloride,4-(Chloromethyl)-(9Ci)
CAS No.	155136-55-3
Molecular Formula	C7H5Cl2NO
Molecular Weight	190.03 g/mol
Synonyms	4-(Chloromethyl)nicotinoyl chloride; 4-(Chloromethyl)pyridine-3-carbonyl chloride; 3-Carbonylchloride-4-(chloromethyl)pyridine; Nicotinoyl chloride, 4-(chloromethyl)-; Isonicotinoyl chloride, 6-(chloromethyl)-; 4-Chloromethylnicotinic acid chloride; 3-Pyridinecarbonyl chloride, 4-(chloromethyl)-; 4-(Chloromethyl)nicotinic acid chloride
EINECS	Contact for details

Quality Control

Every batch of 3-Pyridinecarbonylchloride,4-(Chloromethyl)-(9Ci) is manufactured and tested under strict quality management protocols. We ensure high purity and batch-to-batch consistency through advanced analytical techniques. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.