Description

3-Pyridinecarbonyl Chloride, 4-Methyl- (9Ci) is a versatile and highly reactive chemical building block, specifically an acyl chloride derivative of a methyl-substituted pyridine. Its primary value lies in its role as a key intermediate for introducing the 4-methylnicotinoyl moiety into target molecules, enabling the synthesis of more complex structures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to create active ingredients, ligands, and advanced materials. The CAS number for this compound is 155136-54-2.

Application

This reactive intermediate serves as a critical synthon in various research and industrial synthesis pathways. Its primary applications include:

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in creating amide bonds for potential kinase inhibitors, receptor modulators, and other bioactive molecules.
• Agrochemical Synthesis: Used in the development of advanced pesticides, herbicides, and fungicides that incorporate the pyridine scaffold for enhanced efficacy.
• Ligand and Catalyst Preparation: Employed in organometallic chemistry to synthesize specialized ligands for catalysis and material science applications.
• Chemical Research & Development: A valuable tool in academic and industrial R&D for exploring new chemical entities and reaction methodologies.
• Fine Chemical Production: Serves as a precursor in the multi-step synthesis of complex fine chemicals and specialty materials.

Basic Information

Product Name	3-Pyridinecarbonyl Chloride, 4-Methyl- (9Ci)
CAS No.	155136-54-2
Molecular Formula	C7H6ClNO
Molecular Weight	155.58 g/mol
Synonyms	4-Methylnicotinoyl chloride; 4-Methylpyridine-3-carbonyl chloride; 3-Carbonyl chloride-4-methylpyridine; 4-Picoline-3-carbonyl chloride; Isonicotinoyl chloride, 4-methyl-; 4-Methyl-3-pyridinecarboxylic acid chloride
EINECS	Contact for details

Quality Control

Our 3-Pyridinecarbonyl Chloride, 4-Methyl- (9Ci) is produced under stringent quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the exacting standards required for research and synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic (moisture-sensitive) nature and reactivity as an acid chloride, the material must be stored under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C for long-term stability. Keep away from strong bases, alcohols, and moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.