Description

Malonofungin is a potent antifungal agent belonging to the echinocandin class of compounds. It serves as a critical intermediate in the synthesis of advanced antifungal pharmaceuticals, offering high efficacy against a broad spectrum of fungal pathogens. This compound is essential for pharmaceutical R&D and manufacturing, particularly for organizations developing next-generation treatments for systemic fungal infections. We supply high-purity Malonofungin CAS NO 154032-80-1 to support global innovation in antifungal therapy.

Application

• Pharmaceutical Intermediate: Primary use as a key building block in the synthesis of advanced echinocandin antifungal drugs.
• Antifungal Drug Development: Serves as a reference standard and active scaffold in R&D for novel antifungal agents targeting glucan synthase.
• Biochemical Research: Used in microbiological and pharmacological studies to investigate fungal cell wall biosynthesis and inhibition mechanisms.
• API Manufacturing: Employed in the controlled production of Active Pharmaceutical Ingredients (APIs) for antifungal medications.
• Veterinary Medicine: Potential application in developing antifungal treatments for animal health.

Basic Information

Product Name	Malonofungin
CAS No.	154032-80-1
Molecular Formula	C52H81N7O17
Molecular Weight	1052.24 g/mol
Synonyms	Malonofungin; FR 901379; FR-901379; (4R,5R)-4,5-Dihydroxy-N2-((10R,12R)-10,12-dimethyl-1-oxotetradecyl)-L-ornithyl-L-threonyl-trans-4-hydroxy-L-prolyl-(S)-4-hydroxy-4-(4-hydroxyphenyl)-L-threonyl-trans-3-hydroxy-L-prolyl-(3S)-3-hydroxy-L-homotyrosyl-(1S,2R)-1,2-dihydroxy-2-(4-hydroxyphenyl)ethylamide; Echinocandin derivative FR901379
EINECS	Contact for details

Quality Control

Our Malonofungin is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for pharmaceutical applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by spectroscopic methods, and stringent control of residual solvents and impurities. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 20 ppm
Total Impurities (HPLC)	≤ 2.0%
Single Unknown Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.