Description

Aureobasidin S2B is a potent antifungal compound belonging to the cyclic depsipeptide class, identified by CAS number 153954-73-5. It serves as a critical tool compound for biochemical research, specifically targeting the Sec14 phosphatidylinositol/phosphatidylcholine transfer protein to inhibit fungal growth. This product is essential for researchers and developers in the pharmaceutical and agricultural sectors who are investigating novel antifungal mechanisms and developing next-generation treatments.

Application

• Antifungal Mechanism Research: A key biochemical probe for studying the inhibition of Sec14p, a vital protein in fungal lipid metabolism and vesicle trafficking.
• Pharmaceutical R&D: Serves as a reference standard and lead compound in the discovery and development of new systemic and topical antifungal agents.
• Agricultural Fungicide Development: Used in research to explore its potential and derivatives for protecting crops against pathogenic fungi.
• Microbiology Studies: Employed in laboratory settings to study yeast and fungal genetics, physiology, and resistance mechanisms.
• Cell Biology Tool: Utilized to investigate intracellular lipid transport and membrane dynamics in eukaryotic model systems.
• High-Throughput Screening: Acts as a positive control or benchmark compound in assays designed to identify new antifungal candidates.

Basic Information

Product Name	Aureobasidin S2B
CAS No.	153954-73-5
Molecular Formula	C61H92N8O13
Molecular Weight	1145.4 g/mol
Synonyms	Aureobasidin S2B; Aureobasidin S 2B; AbA S2B; Antibiotic S 2B; Cyclic Depsipeptide Antibiotic S2B; (3S,6R,9S,12R,15S,18S,21S,24S,27S,30S,33S,36S,39S)-9,15,21,27,33,39-Hexabenzyl-3,6,12,18,24,30,36-heptaisobutyl-1,4,7,10,13,16,19,22,25,28,31,34,37,40-tetradecaazacyclotetracontane-2,5,8,11,14,17,20,23,26,29,32,35,38,41-tetradecaone
EINECS	Contact for details

Quality Control

Our Aureobasidin S2B is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and reliability for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant standards for high-purity biochemical reagents to support your critical research and development work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a desiccated environment to maintain stability and potency. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.