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Aureobasidin S1 CAS NO 153954-71-3
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CAS No.:153954-71-3
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
Aureobasidin S1 is a potent antifungal cyclic peptide antibiotic derived from the fungus *Aureobasidium pullulans*. This compound is highly valued for its specific and powerful inhibitory activity against fungal pathogens, making it a critical tool in antifungal research and development. It is primarily utilized by pharmaceutical R&D teams, microbiologists, and agrochemical scientists for studying fungal cell biology and developing novel antifungal agents.
Application
- Antifungal Research & Development: Serves as a key reference standard and active agent in the discovery and screening of new antifungal drugs.
- Mechanism of Action Studies: Used to investigate fungal cell wall biosynthesis and signal transduction pathways due to its specific target (inositol phosphorylceramide synthase).
- Agricultural Fungicide Development: Explored as a lead compound for creating next-generation crop protection agents against plant pathogenic fungi.
- Microbiological Assays: Employed as a selective agent in culture media for fungal strain identification and resistance testing.
- Biochemical Reagent: Utilized in enzymatic studies and as a molecular probe to elucidate sphingolipid metabolism in eukaryotic cells.
- Veterinary Medicine Research: Investigated for potential applications in treating fungal infections in animals.
Basic Information
| Product Name | Aureobasidin S1 |
| CAS No. | 153954-71-3 |
| Molecular Formula | C61H91N9O13 |
| Molecular Weight | 1150.4 g/mol |
| Synonyms | Aureobasidin S1; Aureobasidin S-1; Antibiotic AUR-S1; Cyclo[(2S,4R)-4-hydroxy-2-methyloctanoyl-L-α-aminobutyryl-N-methyl-L-valyl-N-methyl-L-valyl-N-methyl-L-leucyl-L-phenylalanyl-D-prolyl-L-α-aminobutyryl-N-methyl-L-valyl-N-methyl-L-leucyl]; AUR-S1; Aureobasidin S 1 |
| EINECS | Contact for details |
Quality Control
Our Aureobasidin S1 is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC for purity, MS for identity confirmation, and NMR for structural verification. Certificates of Analysis (COA) detailing purity, potency, and impurity profiles are available upon request to ensure it meets the stringent requirements for research and development applications.
Storage
Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and potency. Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white powder |
| Identification (HPLC) | Conforms to reference standard |
| Identification (MS) | Conforms to reference standard |
| Purity (HPLC) | ≥ 95.0% |
| Water Content (KF) | ≤ 5.0% |
| Potency (Microbiological Assay) | ≥ 980 µg/mg |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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