Description

1-(3,5-Difluorophenyl)Ethanol is a versatile fluorinated aromatic alcohol building block of significant importance in advanced organic synthesis. Its value lies in the strategic placement of fluorine atoms on the phenyl ring, which can dramatically influence the lipophilicity, metabolic stability, and binding affinity of target molecules. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of active pharmaceutical ingredients (APIs), particularly in CNS and anti-inflammatory drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides, where the difluorophenyl moiety enhances biological activity.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials, improving their stability and performance.
• Asymmetric Catalysis: Employed as a substrate or ligand precursor in stereoselective synthesis to construct complex chiral molecules.
• Polymer Modification: Acts as a monomer or chain modifier to introduce fluorine-containing aromatic groups into specialty polymers, altering their physical properties.
• Chemical Research: A valuable reagent in academic and industrial R&D for exploring new fluorination chemistry and structure-activity relationships (SAR).

Basic Information

Product Name	1-(3,5-Difluorophenyl)Ethanol
CAS No.	153877-56-6
Molecular Formula	C8H8F2O
Molecular Weight	158.15 g/mol
Synonyms	(3,5-Difluorophenyl)methanol; α,3,5-Trifluorobenzyl Alcohol; 1-(3,5-Difluorophenyl)methanol; 3,5-Difluorobenzyl Alcohol; (3,5-Difluorophenyl)carbinol; 3,5-Difluoro-α-methylbenzyl Alcohol; NSC 339063; 3,5-Difluorobenzylalcohol
EINECS	Contact for details

Quality Control

Our 1-(3,5-Difluorophenyl)Ethanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.