Description

Bexarotene is a synthetic retinoid analog that selectively activates retinoid X receptors (RXRs), a critical mechanism for regulating cell differentiation, proliferation, and apoptosis. This targeted action makes it a valuable active pharmaceutical ingredient (API) for the development of specialized therapeutics. It is primarily utilized by pharmaceutical manufacturers and research institutions focused on oncology and dermatology. Our supply ensures high purity and consistent quality to meet stringent regulatory and research requirements.

Application

• Active Pharmaceutical Ingredient (API) in the formulation of oral and topical medications.
• Primary therapeutic agent for the treatment of cutaneous T-cell lymphoma (CTCL).
• Research and development of novel RXR-targeted therapies for various cancers.
• Investigational compound in preclinical and clinical studies for other oncological indications.
• Key intermediate in advanced pharmaceutical synthesis and process development.
• Reference standard for analytical method development and quality control in pharmaceutical laboratories.

Basic Information

Product Name	Bexarotene
CAS No.	153559-49-0
Molecular Formula	C24H28O2
Molecular Weight	348.48 g/mol
Synonyms	4-[1-(5,6,7,8-Tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)ethenyl]benzoic Acid; Targretin®; LGD1069; Bexarotenum; Bexaroteno; Bexarotène; Bexarotenum [Latin]; Bexaroteno [Spanish]; Bexarotène [French]
EINECS	Contact for details

Quality Control

Our Bexarotene is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, residual solvent analysis, and identification by spectroscopic methods, to ensure it meets high-grade pharmaceutical standards. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with relevant specifications for use as an API.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under conditions that minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.5%
Related Substances (HPLC)	Total impurities ≤1.5%
Single Maximum Impurity	≤0.5%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.