Description

Azido-Peg4-Tetra-Ac-β-D-Glucose is a specialized bifunctional chemical linker featuring a reactive azide group and a tetra-acetylated glucose moiety, connected by a tetraethylene glycol (PEG4) spacer. This compound is engineered to facilitate bioorthogonal conjugation strategies, particularly copper-free click chemistry, enabling the site-specific labeling and modification of biomolecules. It is an essential tool for researchers and developers in the fields of bioconjugation, glycobiology, and pharmaceutical development, where precise attachment of carbohydrate epitopes or probes is required.

Application

• Bioconjugation and Probe Synthesis: Used for the site-specific labeling of proteins, antibodies, and other biomolecules via strain-promoted azide-alkyne cycloaddition (SPAAC).
• Glycobiology Research: Serves as a building block for synthesizing neoglycoconjugates to study carbohydrate-protein interactions and cell surface engineering.
• Drug Delivery Systems: Facilitates the development of targeted drug conjugates by linking therapeutic agents to targeting ligands via the PEG spacer.
• Diagnostic Reagents: Employed in the creation of fluorescent or other detection probes for imaging and diagnostic assays.
• Material Science: Used to functionalize surfaces, nanoparticles, or polymers with sugar motifs for creating bioactive materials.
• Chemical Biology Tool Development: Acts as a key intermediate in the synthesis of more complex chemical probes for cellular studies.

Basic Information

Product Name	Azido-Peg4-Tetra-Ac-β-D-Glucose
CAS No.	153252-44-9
Molecular Formula	C₂₆H₄₃N₃O₁₄
Molecular Weight	621.64 g/mol
Synonyms	2-(2-(2-(2-Azidoethoxy)ethoxy)ethoxy)ethyl 2,3,4,6-tetra-O-acetyl-β-D-glucopyranoside; N3-PEG4-Tetraacetyl-β-D-glucose; Azido-PEG4-tetraacetylglucose; 1-Azido-3,6,9,12-tetraoxapentadecan-15-yl 2,3,4,6-tetra-O-acetyl-β-D-glucopyranoside; β-D-Glucopyranoside, 2,3,4,6-tetra-O-acetyl-, 2-[2-[2-[2-(azidoethoxy)ethoxy]ethoxy]ethoxy]ethyl; Azido-PEG4-β-D-GlcNAc(Ac)₃ (common misnomer); Azido-PEG4-Glc(Ac)₄
EINECS	Contact for details

Quality Control

Our Azido-Peg4-Tetra-Ac-β-D-Glucose is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and structural integrity. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request. We are committed to meeting the stringent requirements of research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. Allow the sealed vial to equilibrate to room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid or viscous oil
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.