Description

4'--C-Methyluridine is a chemically modified nucleoside analog, a key building block in advanced pharmaceutical and biochemical research. Its unique structure, featuring a methyl group at the 4'-carbon position, makes it a critical intermediate for the synthesis of novel therapeutic agents and molecular probes. This compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and diagnostic sectors developing next-generation antiviral drugs, mRNA therapeutics, and nucleotide-based prodrugs.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel nucleoside-based antiviral and anticancer agents.
• Biochemical Research: Used as a modified building block in oligonucleotide synthesis to study RNA structure, function, and stability.
• Pro-drug Development: Serves as a key component in the design of nucleotide pro-drugs aimed at improving cellular uptake and therapeutic efficacy.
• mRNA Technology: Potential application in the research and development of modified mRNA for therapeutic and vaccine platforms.
• Diagnostic Probe Synthesis: Utilized in creating labeled nucleotides for use in diagnostic assays and genomic sequencing.
• Medicinal Chemistry: A valuable scaffold for structure-activity relationship (SAR) studies to optimize drug potency and selectivity.

Basic Information

Product Name	4'--C-Methyluridine
CAS No.	153186-26-6
Molecular Formula	C10H14N2O6
Molecular Weight	258.23 g/mol
Synonyms	4'-C-Methyluridine; 1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)-4-methyltetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione; 4'-Methyluridine; 4'-C-Methyl-1-β-D-ribofuranosyluracil; Uridine, 4'-C-methyl-
EINECS	Contact for details

Quality Control

Our 4'--C-Methyluridine is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and moisture content. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or cGMP-grade requirements. Specifications can be tailored to meet specific project needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive. Keep the container tightly sealed in a dry environment to prevent degradation from moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.