Description

N(6)-(4-Aminobenzyl)Adenosine-5'-n-Methyluronamide is a chemically modified adenosine derivative designed for advanced biochemical research and pharmaceutical development. This compound is valued for its role as a potent and selective agonist for adenosine receptors, particularly the A3 subtype, making it a critical tool for studying cardiovascular, neurological, and inflammatory pathways. It is primarily utilized by research institutions, pharmaceutical R&D departments, and biotechnology companies engaged in drug discovery and signal transduction research.

Application

• Pharmacological Research: Serves as a key reference standard and selective agonist in adenosine receptor (A3) binding and functional assays.
• Drug Discovery & Development: Used as a lead compound or intermediate in the synthesis of novel therapeutics targeting cardiovascular diseases, neuroprotection, and inflammatory conditions.
• Biochemical Pathway Analysis: A vital tool for investigating cAMP-mediated signaling pathways and cellular responses in model systems.
• Academic Research: Employed in university and institutional labs for fundamental studies on purinergic signaling and receptor pharmacology.
• Diagnostic Development: Potential use in developing assays and kits for receptor characterization and screening.

Basic Information

Product Name	N(6)-(4-Aminobenzyl)Adenosine-5'-n-Methyluronamide
CAS No.	152918-20-2
Molecular Formula	C19H24N8O4
Molecular Weight	428.45 g/mol
Synonyms	N6-(4-Aminobenzyl)adenosine-5'-N-methyluronamide; 4-Aminobenzyladenosine-5'-N-methylcarboxamide; AB-MECA; N6-(4-Aminobenzyl)-5'-N-methylcarboxamidoadenosine; A3 Adenosine Receptor Agonist AB-MECA; IB-MECA analog; Adenosine, N-[4-(aminomethyl)phenyl]methyl]-5'-(methylaminocarbonyl)-
EINECS	Contact for details

Quality Control

Our N(6)-(4-Aminobenzyl)Adenosine-5'-n-Methyluronamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and assay is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. Due to its hygroscopic (moisture-sensitive) nature, the container should be allowed to reach room temperature before opening to prevent condensation. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.