Description

6-Benzo[A]Pyrenylisothiocyanate CAS NO 152832-13-8 is a high-purity, reactive chemical derivative of benzo[a]pyrene, a polycyclic aromatic hydrocarbon. This compound is a critical reagent for advanced analytical chemistry and biochemical research, enabling precise labeling and detection. It is primarily utilized by research institutions, diagnostic manufacturers, and quality control laboratories specializing in environmental monitoring, toxicology studies, and biomarker development.

Application

• Biomarker Derivatization Agent: Used to create fluorescent or detectable conjugates of polycyclic aromatic hydrocarbon (PAH) metabolites for sensitive bioanalytical assays.
• HPLC & LC-MS/MS Reference Standard: Serves as a critical standard and derivatization reagent for the accurate quantification of benzo[a]pyrene and related compounds in complex matrices.
• Environmental Analysis: Employed in the detection and study of PAH-DNA adducts, aiding in the assessment of environmental contamination and carcinogenic risk.
• Biochemical Research: Acts as a key intermediate in synthesizing probes for studying enzyme activity, DNA damage, and cellular response pathways related to PAH exposure.
• Diagnostic Kit Development: Utilized in the manufacturing of research-use-only (RUO) and diagnostic kits designed to detect exposure to carcinogenic hydrocarbons.
• Toxicology Studies: Essential for in vitro and in vivo research investigating the metabolic activation and binding mechanisms of potent carcinogens.

Basic Information

Product Name	6-Benzo[A]Pyrenylisothiocyanate
CAS No.	152832-13-8
Molecular Formula	C23H11NS
Molecular Weight	333.41 g/mol
Synonyms	6-BPITC; Benzo[a]pyrene-6-isothiocyanate; 6-Isothiocyanatobenzo[a]pyrene; 6-Benzo(a)pyrenyl isothiocyanate; NSC 339539; 6-BAP-ITC; 1-Isothiocyanatobenzo[a]pyrene (positional isomer); B[a]P-6-NCS
EINECS	Contact for details

Quality Control

Every batch of 6-Benzo[A]Pyrenylisothiocyanate is manufactured under strict quality management protocols and undergoes comprehensive analytical testing. We guarantee high chemical purity and lot-to-lot consistency suitable for sensitive research and analytical applications. A detailed Certificate of Analysis (COA) providing purity, identity confirmation, and impurity profiles is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed in a desiccated environment to prevent degradation. For long-term storage, consider inert atmosphere conditions.

Specification

Item	Specification
Appearance	Yellow to light brown solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Melting Point	Contact for details
Water Content (KF)	≤ 1.0%
Related Substances (HPLC)	Individual impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.