Description

4'-Methyladenosine CAS NO 152540-76-6 is a chemically modified nucleoside analog, where a methyl group is introduced at the 4' position of the ribose sugar. This structural modification is of significant interest in biochemical and pharmaceutical research for studying enzyme mechanisms and developing novel therapeutic agents. It is primarily utilized by research institutions and pharmaceutical companies engaged in nucleoside chemistry, antiviral drug discovery, and molecular biology.

Application

• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies, particularly for methyltransferases and other nucleoside-processing enzymes.
• Antiviral Drug Development: Serves as a key intermediate or analog in the synthesis of potential antiviral and anticancer nucleoside prodrugs.
• Molecular Biology: Employed in the study of RNA structure, function, and modification (epitranscriptomics).
• Pharmaceutical Intermediates: Acts as a building block for the synthesis of more complex modified nucleosides and nucleotides.
• Standards and References: Used as a certified reference material (CRM) for analytical method development and quality control in related APIs.

Basic Information

Product Name	4'-Methyladenosine
CAS No.	152540-76-6
Molecular Formula	C11H15N5O4
Molecular Weight	281.27 g/mol
Synonyms	4'-C-Methyladenosine; 4'-Methyl-Adenosine; Adenosine, 4'-methyl-; 9-[(4-Methyl-β-D-ribofuranosyl)]adenine; 4'-Methyl-A; 1-(4-Methyl-β-D-ribofuranosyl)adenine; 4'-C-Methyl-A; 4'-Methyl-β-D-adenosine
EINECS	Contact for details

Quality Control

Our 4'-Methyladenosine is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and moisture. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and light-sensitive (store away from light). For long-term storage, consider desiccant and under inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.