Description

1-(2-Deoxy-2-C-Fluoromethylarabinofuranosyl)Cytosine is a fluorinated nucleoside analog of significant interest in advanced pharmaceutical research and development. This compound is valued for its potential as a key synthetic intermediate or active pharmaceutical ingredient (API) in the creation of novel antiviral and anticancer therapeutics. It is primarily required by research institutions, pharmaceutical companies, and fine chemical manufacturers engaged in the synthesis of next-generation nucleoside-based drugs. The compound, identified by CAS No. 152502-85-7, demands stringent quality control to ensure its efficacy and safety in sensitive biological applications.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel antiviral and anticancer nucleoside analogs.
• Antiviral Drug Research: Investigated for its potential activity against a range of viral pathogens due to its modified sugar moiety.
• Oncology Research: Used in preclinical studies to develop chemotherapeutic agents that target DNA synthesis in cancer cells.
• Biochemical Tool: Employed in enzymatic studies to understand the substrate specificity of nucleoside kinases and polymerases.
• Process Chemistry: Utilized in scale-up and optimization studies for the commercial production of specialty active pharmaceutical ingredients (APIs).
• Reference Standard: Acts as a high-purity analytical standard for quality control and regulatory submissions in drug development.

Basic Information

Product Name	1-(2-Deoxy-2-C-Fluoromethylarabinofuranosyl)Cytosine
CAS No.	152502-85-7
Molecular Formula	C₁₀H₁₃FN₄O₄
Molecular Weight	272.23 g/mol
Synonyms	2'-Deoxy-2'-C-fluoromethylcytidine arabinoside; 2'-C-Fluoromethylcytidine; 1-(2-Deoxy-2-fluoro-2-C-methyl-β-D-arabinofuranosyl)cytosine; 2'-C-Fluoromethyl-ara-C; Fluoromethyl-araC; 152502-85-7; FC-araC
EINECS	Contact for details

Quality Control

Our 1-(2-Deoxy-2-C-Fluoromethylarabinofuranosyl)Cytosine is manufactured under strict quality systems suitable for pharmaceutical research. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for sensitive applications. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and analytical methods is provided with every shipment. We support compliance with ICH guidelines for impurities and stability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.