Description

Imatinib is a potent and selective small-molecule tyrosine kinase inhibitor that targets specific oncogenic proteins. This high-purity active pharmaceutical ingredient (API) is critical for the development and production of targeted cancer therapies. It is primarily required by pharmaceutical manufacturers and research institutions engaged in oncology drug development and formulation.

Application

• Pharmaceutical API: Primary active ingredient in targeted cancer therapy formulations.
• Oncology Research: Key reference standard and biochemical tool for studying BCR-ABL, c-KIT, and PDGFR kinase pathways.
• Generic Drug Manufacturing: Sourcing for the production of generic versions of tyrosine kinase inhibitor medications.
• Preclinical & Clinical Development: Used in the synthesis of drug candidates for pharmacokinetic and pharmacodynamic studies.
• Analytical Standard: Serves as a high-purity standard for HPLC, LC-MS, and other quality control assays.
• Formulation Development: Used in the development of various dosage forms, including tablets and capsules.

Basic Information

Product Name	Imatinib
CAS No.	152459-95-5
Molecular Formula	C₂₉H₃₁N₇O
Molecular Weight	493.60 g/mol
Synonyms	Imatinib Mesylate; STI571; CGP 57148B; Glivec (Trade Name); Gleevec (Trade Name); 4-[(4-Methyl-1-piperazinyl)methyl]-N-[4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]benzamide; Imatinib free base
EINECS	Contact for details

Quality Control

Our Imatinib is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and potency meet stringent pharmaceutical standards. Certificates of Analysis (COA) detailing specifications such as assay, related substances, residual solvents, and heavy metals are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time conforms to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Related Substances (HPLC)	Total impurities ≤ 1.0%
Individual Unknown Impurity	≤ 0.10%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.