Description

Levodropropizine n-Oxide is a key pharmaceutical intermediate and metabolite of the antitussive agent levodropropizine. This compound is of significant interest for research and development within the pharmaceutical industry, particularly for studies related to drug metabolism, pharmacokinetics, and the synthesis of novel therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories, analytical service providers, and manufacturers engaged in the production of advanced active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis and research of antitussive (cough suppressant) medications.
• Metabolite Reference Standard: Used as an analytical standard in bioanalytical studies to identify and quantify drug metabolites in biological samples.
• Pharmacokinetic Research: Essential for studies investigating the absorption, distribution, metabolism, and excretion (ADME) profiles of levodropropizine.
• Process Development & Validation: Employed in the development and validation of manufacturing processes for pharmaceutical actives.
• Quality Control & Analytical Testing: Acts as a high-purity reference material in HPLC, LC-MS, and other chromatographic methods for impurity profiling and assay determination.
• Regulatory Submission Support: Provides necessary data and reference compounds for regulatory filings with agencies such as the FDA and EMA.

Basic Information

Product Name	Levodropropizine n-Oxide
CAS No.	152237-40-6
Molecular Formula	C13H20N2O2
Molecular Weight	236.31 g/mol
Synonyms	(-)-Dropropizine N-Oxide; (S)-3-(4-Phenyl-1-piperazinyl)-1,2-propanediol 1-Oxide; Levodropropizine N-Oxide; Levodropropizine Oxide; (S)-Dropropizine N-Oxide
EINECS	Contact for details

Quality Control

Our Levodropropizine n-Oxide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification, assay, and impurity profiling via advanced techniques like HPLC and NMR, to ensure it meets the high-purity standards required for pharmaceutical research. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0% Any single impurity ≤0.5%
Residual Solvents (GC)	Complies with ICH guidelines
Loss on Drying	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.