Description

Penehyclidine Hcl (Mixture Of Isomers) is a synthetic anticholinergic agent with significant pharmacological activity. This compound is valued for its role as a key intermediate in the research and development of novel pharmaceutical agents targeting the muscarinic acetylcholine receptor. It is primarily required by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in the synthesis of advanced therapeutic candidates. The product is supplied as a high-purity material suitable for critical development and scale-up processes.

Application

• Pharmaceutical Intermediate: Critical building block in the synthetic pathway for novel anticholinergic drugs.
• Biomedical Research: Used as a reference standard or active agent in pharmacological studies investigating muscarinic receptor modulation.
• Preclinical Development: Serves as a key material for formulation studies, pharmacokinetic profiling, and toxicology assessments of new drug candidates.
• Process Chemistry: Employed in route scouting, optimization, and scale-up activities within fine chemical and API manufacturing.
• Analytical Standard: Provides a qualified standard for method development and validation in quality control laboratories (HPLC, GC, NMR).

Basic Information

Product Name	Penehyclidine Hcl (Mixture Of Isomers)
CAS No.	151937-76-7
Molecular Formula	C20H31NO3•HCl
Molecular Weight	369.93 g/mol (free base: 333.47 g/mol)
Synonyms	Penehyclidine Hydrochloride; (±)-3-(2-Cyclopentyl-2-hydroxy-2-phenylacetoxy)quinuclidine Hydrochloride; 1-Cyclopentyl-1-hydroxy-1-phenyl-3-(1-azabicyclo[2.2.2]oct-3-yl)propyl acetate hydrochloride; Penehyclidine; PHC; CAS 151937-76-7
EINECS	Contact for details

Quality Control

Our Penehyclidine Hcl is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing including HPLC for purity and isomer ratio, identification by spectroscopic methods (IR, NMR), and tests for residual solvents and heavy metals. Certificates of Analysis (COA) detailing all specifications and test results are provided to ensure traceability and compliance with your research or development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Isomer Ratio	Specified upon request
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.