Description

Oxamflatin is a potent and selective synthetic inhibitor of histone deacetylase (HDAC) enzymes, a key target in epigenetic research and therapeutic development. This compound is crucial for modulating gene expression and cellular processes, making it an essential tool for advancing biomedical research. It is primarily utilized by pharmaceutical R&D teams, academic researchers, and biotechnology companies focused on oncology, neurology, and the discovery of novel epigenetic therapies.

Application

• Biomedical Research: A critical tool for studying histone deacetylation, chromatin remodeling, and epigenetic regulation in cellular models.
• Drug Discovery & Development: Used as a reference standard and active pharmaceutical ingredient (API) in preclinical studies for novel HDAC inhibitor therapies.
• Oncology Research: Investigated for its potential to induce cell cycle arrest, differentiation, and apoptosis in various cancer cell lines.
• Neurological Disease Studies: Applied in research models for neurodegenerative conditions where epigenetic dysregulation is implicated.
• Biochemical Assays: Serves as a potent control compound in high-throughput screening (HTS) and enzymatic activity assays targeting HDACs.
• Academic & Institutional Research: Supports fundamental research in molecular biology, genetics, and pharmacology.

Basic Information

Product Name	Oxamflatin
CAS No.	151720-43-3
Molecular Formula	C₁₄H₁₈N₂O₃
Molecular Weight	262.31 g/mol
Synonyms	Oxamflatin; [2E]-N-Hydroxy-2-[4-[[(2S)-2-[(hydroxyamino)carbonyl]-1-pyrrolidinyl]sulfonyl]phenyl]ethenecarboxamide; (2E)-N-Hydroxy-3-[4-[(2S)-2-(hydroxycarbamoyl)pyrrolidin-1-yl]sulfonylphenyl]prop-2-enamide; HDAC Inhibitor VIII; HDAC Inhibitor, Oxamflatin; NSC 354961
EINECS	Contact for details

Quality Control

Our Oxamflatin is manufactured under strict quality management systems to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards for research chemicals, ensuring reliable performance in your experimental workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability. For long-term storage, consider desiccants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.