Description

5'-N-Ethylcarboxamidoadenosine is a potent and selective adenosine A2A receptor agonist, a key compound in cardiovascular and neurological research. Its high specificity makes it an invaluable pharmacological tool for studying receptor signaling pathways, inflammation, and neuroprotection. This product is essential for research and development laboratories in the pharmaceutical and biotechnology sectors, particularly those focused on developing novel therapeutics for conditions like Parkinson's disease, ischemia, and inflammatory disorders.

Application

• Pharmacological Research: Used as a reference standard and selective agonist in studies of adenosine A2A receptor function and signaling.
• Drug Discovery & Development: Serves as a critical lead compound or biochemical tool in screening assays for new cardiovascular and CNS-targeting drugs.
• Neurological Studies: Applied in experimental models to investigate its neuroprotective effects and potential in treating Parkinson's disease and other neurodegenerative conditions.
• Cardiovascular Research: Utilized to study vasodilation, coronary blood flow regulation, and cardioprotective mechanisms.
• Inflammation & Immunology: Employed in research exploring the role of adenosine receptors in modulating immune responses and inflammatory pathways.
• Biochemical Assays: Acts as a high-purity ligand in receptor binding assays and functional cellular tests.

Basic Information

Product Name	5'-N-Ethylcarboxamidoadenosine
CAS No.	151362-68-4
Molecular Formula	C13H18N6O5
Molecular Weight	338.32 g/mol
Synonyms	NECA; 5'-(N-Ethylcarboxamido)adenosine; 2-[6-Amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]purin-2-yl]-N-ethylacetamide; Adenosine, 5'-(N-ethylcarboxamide)-; CGS 21680C; A2A Adenosine Receptor Agonist NECA
EINECS	Contact for details

Quality Control

Every batch of 5'-N-Ethylcarboxamidoadenosine is manufactured under strict quality management systems and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) with each shipment, detailing results from HPLC, NMR, and mass spectrometry. Our quality commitment aligns with standards expected for pharmaceutical research materials.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This compound is hygroscopic (moisture-sensitive); allow the sealed vial to equilibrate to room temperature before opening to minimize condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.