Description

1,3-Dioxolo4,5-Cpyridine-4-Methanol, Hexahydro-7-Hydroxy-2,2-Dimethyl-, 3As-(3A.Alpha.,4.Beta.,7.Alpha.,7A.Alpha.)- is a high-purity, complex heterocyclic building block with significant synthetic utility. This compound is valued for its rigid, fused bicyclic structure and multiple functional handles, making it a critical intermediate in advanced organic synthesis. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and other fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block in the synthesis of complex drug candidates, particularly those targeting the central nervous system.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where its unique structure can contribute to novel modes of action.
• Academic & R&D Laboratories: Employed in methodological studies and the construction of complex natural product analogs or molecular scaffolds for biological screening.
• Fine Chemical Synthesis: Acts as a precursor for specialty chemicals, dyes, and advanced materials requiring specific stereochemistry and functional groups.
• Ligand and Catalyst Development: Its structure can be modified to create novel chiral ligands or organocatalysts for asymmetric synthesis.

Basic Information

Product Name	1,3-Dioxolo4,5-Cpyridine-4-Methanol, Hexahydro-7-Hydroxy-2,2-Dimethyl-, 3As-(3A.Alpha.,4.Beta.,7.Alpha.,7A.Alpha.)-
CAS No.	151252-19-6
Molecular Formula	C11H19NO4
Molecular Weight	229.27 g/mol
Synonyms	Hexahydro-7-hydroxy-2,2-dimethyl-1,3-dioxolo[4,5-c]pyridine-4-methanol (3aα,4β,7α,7aα)-; (3aR,4S,7R,7aS)-Hexahydro-7-hydroxy-2,2-dimethyl-1,3-dioxolo[4,5-c]pyridine-4-methanol; 4-Piperidinemethanol, 1,3-dioxolo[4,5-c]pyridine derivative; A complex hexahydro-1,3-dioxolo[4,5-c]pyridine derivative; Chiral fused bicyclic amino alcohol.
EINECS	Contact for details

Quality Control

Our 1,3-Dioxolo4,5-Cpyridine-4-Methanol, Hexahydro-7-Hydroxy-2,2-Dimethyl-, 3As-(3A.Alpha.,4.Beta.,7.Alpha.,7A.Alpha.)- is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.