Description

Terbinafine is a synthetic allylamine antifungal agent widely recognized for its potent activity against dermatophytes and other fungi. Its primary value lies in its fungicidal mechanism of action, which inhibits squalene epoxidase, a key enzyme in ergosterol biosynthesis, leading to fungal cell death. This makes it an essential active pharmaceutical ingredient (API) for manufacturers of topical and oral antifungal medications targeting conditions like athlete's foot, ringworm, and onychomycosis.

Application

• Pharmaceutical API: Core ingredient in prescription and over-the-counter antifungal creams, gels, sprays, and oral tablets.
• Dermatological Preparations: Used in formulations for treating tinea pedis (athlete's foot), tinea cruris (jock itch), tinea corporis (ringworm), and cutaneous candidiasis.
• Onychomycosis Treatment: Key component in systemic and topical treatments for fungal nail infections.
• Veterinary Antifungals: Incorporated into topical solutions and shampoos for treating fungal skin infections in animals.
• Research & Development: Serves as a reference standard and building block in microbiological research and new antifungal drug development.

Basic Information

Product Name	Terbinafine
CAS No.	151222-50-3
Molecular Formula	C21H25N
Molecular Weight	291.43 g/mol
Synonyms	(2E)-6,6-Dimethyl-2-hepten-4-yn-1-yl](2-naphthyl)methylamine; Terbinafinum; Terbinafina; SF 86-327; Lamisil (brand name); TDT 067 (code); Allylamine antifungal; (E)-N-(6,6-Dimethyl-2-hepten-4-ynyl)-N-methyl-1-naphthalenemethanamine
EINECS	Contact for details

Quality Control

Our Terbinafine is manufactured under strict quality management systems, targeting compliance with major pharmacopoeial standards such as USP and EP. Every batch undergoes comprehensive analytical testing including identification, assay, impurity profiling, and residual solvent analysis to ensure it meets the stringent requirements for pharmaceutical active ingredients. A Certificate of Analysis (COA) documenting all test results is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Related Substances (HPLC)	Total impurities ≤ 1.0% Any individual impurity ≤ 0.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.