Description

Cyclobutanecarbonyl Chloride, 1-(4-Fluorophenyl)- (9Ci) is a high-purity, specialized organic intermediate featuring a cyclobutane ring and an acid chloride functional group. This compound is valued for its role as a key building block in the synthesis of complex molecules, particularly in pharmaceutical research and development. It is primarily sought by R&D chemists and process development scientists in the life sciences sector for constructing novel active pharmaceutical ingredients (APIs) and other fine chemicals.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where the fluorophenyl and cyclobutane motifs can contribute to biological activity.
• Material Science: Serves as a monomer or cross-linking agent in the research of advanced polymers with specific thermal or mechanical properties.
• Chemical Synthesis: Employed in academic and industrial laboratories for method development and the construction of complex, sterically hindered molecular architectures.
• Ligand & Catalyst Development: Utilized to create novel ligands for asymmetric catalysis or metal-organic frameworks (MOFs).

Basic Information

Product Name	Cyclobutanecarbonyl Chloride, 1-(4-Fluorophenyl)- (9Ci)
CAS No.	151157-29-8
Molecular Formula	C11H10ClFO
Molecular Weight	212.65 g/mol
Synonyms	1-(4-Fluorophenyl)cyclobutanecarbonyl chloride; 4-Fluoro-α-(1-oxocyclobutyl)benzenecarbonyl chloride; 1-(4-Fluorophenyl)cyclobutane-1-carbonyl chloride; 1-(p-Fluorophenyl)cyclobutanecarboxylic acid chloride; Cyclobutanecarbonyl chloride, 1-(4-fluorophenyl)-; 1-(4-Fluorophenyl)cyclobutanecarboxylic acid, chloride
EINECS	Contact for details

Quality Control

Our Cyclobutanecarbonyl Chloride, 1-(4-Fluorophenyl)- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC analysis, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical characteristics is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature and reactivity as an acid chloride, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong bases, oxidizers, and moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.