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11-(5'-Azidosalicylamido)Undecanoic Acid CAS NO 151059-75-5


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CAS No.:151059-75-5

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

11-(5'-Azidosalicylamido)Undecanoic Acid is a specialized bifunctional chemical linker featuring a photoreactive azido group and a carboxylic acid terminus. This compound is engineered for the site-specific conjugation of biomolecules, enabling the creation of stable, covalent bonds under controlled conditions. It is an essential tool for researchers and developers in the fields of bioconjugation, proteomics, and advanced materials science, where precise molecular attachment is critical.

Application

  • Bioconjugation and Protein Labeling: Used to covalently attach proteins, peptides, or antibodies to surfaces, nanoparticles, or other biomolecules via its photoreactive azide group.
  • Surface Functionalization: Key reagent for modifying material surfaces (e.g., gold, silica, polymers) with bioactive ligands for biosensor and microarray development.
  • Crosslinking Agent: Serves as a heterobifunctional crosslinker to study protein-protein interactions or to create stable biomaterial networks.
  • Probe Synthesis: Facilitates the synthesis of fluorescent, affinity, or spectroscopic probes for cellular imaging and diagnostic assays.
  • Polymer and Hydrogel Modification: Incorporated into polymer backbones to introduce bio-recognition sites for creating smart, responsive biomaterials.
  • Pharmaceutical Research: Employed in the development of antibody-drug conjugates (ADCs) and targeted drug delivery systems.

Basic Information

Product Name 11-(5'-Azidosalicylamido)Undecanoic Acid
CAS No. 151059-75-5
Molecular Formula C18H27N5O4
Molecular Weight 377.44 g/mol
Synonyms 5-Azido-2-[[11-(carboxy)undecanoyl]amino]benzoic Acid; N-(5-Azido-2-hydroxybenzoyl)-11-aminoundecanoic Acid; 11-[(5-Azido-2-hydroxybenzoyl)amino]undecanoic Acid; ASA-Undecanoic Acid; Azidosalicylamidoundecanoic Acid; Heterobifunctional Crosslinker, Azido-Carboxyl; Photoreactive Carboxylic Acid Linker
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Quality Control

Every batch of 11-(5'-Azidosalicylamido)Undecanoic Acid is subjected to rigorous analytical testing to ensure high purity and consistent performance. Our quality assurance protocols include advanced chromatographic and spectroscopic methods. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant. The compound is light-sensitive (store away from light) and hygroscopic (moisture-sensitive). Allow the container to reach room temperature before opening to minimize moisture condensation. For long-term stability, store under an inert atmosphere.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 95%
Water Content (KF) ≤ 1.0%
Solubility Soluble in DMSO, DMF; Slightly soluble in methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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