Description

2'-C-Methyluridine Diphosphate is a modified nucleoside diphosphate analog of significant interest in pharmaceutical research and development. This compound serves as a critical building block and biochemical tool for investigating and inhibiting RNA-dependent RNA polymerases. It is primarily utilized by research institutions and pharmaceutical companies engaged in the discovery of novel antiviral therapeutics, particularly for RNA viruses such as Hepatitis C Virus (HCV).

Application

• Antiviral Drug Discovery: A key intermediate and biochemical probe in the research and development of nucleoside analog inhibitors targeting viral RNA polymerases.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic assays to study the mechanism and kinetics of viral replication enzymes.
• Pharmaceutical Synthesis: Serves as a vital precursor in the synthetic pathway for advanced antiviral prodrug candidates.
• Virology Studies: Employed in vitro to understand viral resistance mechanisms and to evaluate the efficacy of potential therapeutic compounds.
• Medicinal Chemistry: Provides a scaffold for structure-activity relationship (SAR) studies to optimize potency and selectivity of drug candidates.

Basic Information

Product Name	2'-C-Methyluridine Diphosphate
CAS No.	150993-73-0
Molecular Formula	C11H17N2O14P2
Molecular Weight	463.20 g/mol
Synonyms	2'-C-Methyluridine 5'-diphosphate; 2'-Methyluridine diphosphate; 2'-C-Me-UDP; 1-[(2R,3R,4S,5R)-3,4-Dihydroxy-5-[[hydroxy(phosphonooxy)phosphinyl]oxymethyl]-3-methyloxolan-2-yl]pyrimidine-2,4-dione; UDP analog, 2'-C-methyl; 2'-C-Methyl-UDP
EINECS	Contact for details

Quality Control

Our 2'-C-Methyluridine Diphosphate is manufactured under strict quality systems to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation. A Certificate of Analysis (COA) detailing specifications and test results is provided with every shipment to guarantee compliance with your research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.