Description

(4-Cyano-Phenyl)-Phosphonic Acid Diethyl Ester is a high-value organophosphorus intermediate featuring a cyano-substituted aromatic ring. This compound matters for its unique bifunctional structure, combining a phosphonate ester group for metal chelation or ligand formation with a reactive nitrile moiety for further chemical transformations. It is primarily needed by R&D chemists and process engineers in the pharmaceutical and agrochemical industries for synthesizing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of kinase inhibitors, antiviral agents, and other bioactive molecules where the phosphonate group can mimic phosphate esters.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and plant growth regulators.
• Ligand Precursor: Serves as a starting material for creating specialized phosphonate-based ligands used in catalysis and metal-organic frameworks (MOFs).
• Material Science: Employed in the production of flame retardants, corrosion inhibitors, and specialty polymers.
• Chemical Research: A versatile reagent for organic synthesis, particularly in Horner-Wadsworth-Emmons (HWE) olefination reactions and cross-coupling methodologies.

Basic Information

Product Name	(4-Cyano-Phenyl)-Phosphonic Acid Diethyl Ester
CAS No.	150805-64-4
Molecular Formula	C11H14NO3P
Molecular Weight	239.21 g/mol
Synonyms	Diethyl (4-Cyanophenyl)phosphonate; (4-Cyanophenyl)phosphonic Acid Diethyl Ester; p-Cyanophenylphosphonic Acid Diethyl Ester; Diethyl p-Cyanobenzylphosphonate; Diethyl 4-Cyanobenzylphosphonate; Phosphonic acid, P-(4-cyanophenyl)-, diethyl ester; Diethyl (4-Cyanobenzyl)phosphonate
EINECS	Contact for details

Quality Control

Every batch of (4-Cyano-Phenyl)-Phosphonic Acid Diethyl Ester is manufactured under strict quality management systems. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with industry standards and customer-specific requirements. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. The container must be kept tightly closed to prevent moisture absorption.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.