Description

N6-(Diisobutylaminomethylidene)-2'-Deoxyisoguanosine is a chemically modified nucleoside analog, a key building block in advanced pharmaceutical research and development. This compound is valued for its role as a versatile intermediate in the synthesis of novel therapeutic agents, particularly in the fields of antiviral and anticancer drug discovery. It is primarily sought after by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in developing next-generation nucleotide-based therapies.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel nucleoside analog prodrugs and active pharmaceutical ingredients (APIs).
• Antiviral Drug Research: Used in the development of experimental antiviral compounds targeting viral polymerases and replication mechanisms.
• Oncology Research: Serves as a building block for creating potential chemotherapeutic agents that interfere with DNA synthesis and repair in cancer cells.
• Biochemical Probe Development: Utilized in the design of molecular probes for studying enzyme kinetics and nucleic acid interactions.
• Medicinal Chemistry: A valuable scaffold for structure-activity relationship (SAR) studies to optimize drug potency and selectivity.
• Process Chemistry & Scale-up: Employed in the development and optimization of scalable synthetic routes for GMP-grade material production.

Basic Information

Item	Details
Product Name	N6-(Diisobutylaminomethylidene)-2'-Deoxyisoguanosine
CAS No.	150678-55-0
Molecular Formula	C₁₉H₃₀N₆O₄
Molecular Weight	406.48 g/mol
Synonyms	2'-Deoxy-N6-(diisobutylaminomethylene)isoguanosine; N6-(Diisobutylaminomethylene)-2'-deoxyisoguanosine; 2'-Deoxyisoguanosine, N6-(diisobutylaminomethylene)-; 9-[(2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)oxolan-2-yl]-6-(diisobutylaminomethylidene)-1H-purin-2-one; Modified Nucleoside; Isoguanosine Derivative
EINECS	Contact for details

Quality Control

Our N6-(Diisobutylaminomethylidene)-2'-Deoxyisoguanosine is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment. We support development projects requiring material aligned with ICH guidelines for impurities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95.0%
Assay	≥ 97.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH limits

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.