Description

Bicyclo[3.1.1]Heptane-2-Carbonyl Chloride, 6,6-Dimethyl-, [1S-(1Alpha,2Beta,5Alpha)]- (9Ci) is a high-purity, stereochemically defined chiral building block essential for advanced organic synthesis. Its rigid bicyclic pinane structure and reactive acid chloride group make it a valuable intermediate for constructing complex molecules with precise spatial orientation. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the development of new active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting CNS and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where its specific stereochemistry can influence biological activity and environmental profile.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing specialized chiral ligands and organocatalysts used in asymmetric synthesis.
• Fragrance and Flavor Chemistry: The pinane skeleton is a valuable starting point for creating novel, high-value odorants and flavor compounds.
• Material Science Research: Employed in the synthesis of monomers for specialty polymers with unique thermal or mechanical properties derived from the bicyclic framework.
• Academic and R&D Laboratories: A critical reagent for methodological studies in organic synthesis and stereochemistry at universities and corporate R&D centers.

Basic Information

Item	Details
Product Name	Bicyclo[3.1.1]Heptane-2-Carbonyl Chloride, 6,6-Dimethyl-, [1S-(1Alpha,2Beta,5Alpha)]- (9Ci)
CAS No.	150614-87-2
Molecular Formula	C10H15ClO
Molecular Weight	186.68 g/mol
Synonyms	(1S,2R,5S)-6,6-Dimethylbicyclo[3.1.1]heptane-2-carbonyl chloride; (-)-cis-Myrtanoyl chloride; (1S,2R,5S)-(-)-Myrtanoyl chloride; Pinane-2-carbonyl chloride, (1S,2R,5S)-(-)-; (1S,2R,5S)-Pinane-2-carbonyl chloride; Chiral Pinanoyl Chloride; (1S,2R,5S)-6,6-Dimethyl-2-bicyclo[3.1.1]heptanecarbonyl chloride
EINECS	Contact for details

Quality Control

Every batch of our Bicyclo[3.1.1]Heptane-2-Carbonyl Chloride is produced and tested under strict quality management systems. We ensure high chiral purity and chemical integrity through advanced analytical techniques including chiral HPLC, GC, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles is provided with each shipment to guarantee compliance with your research and production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic and highly volatile nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) at temperatures between 2°C and 8°C for long-term stability. Allow the sealed container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (Karl Fischer)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.