Description

Bicyclo[3.1.1]Heptane-2-Carbonyl Chloride, 6,6-Dimethyl-, [1S-(1Alpha,2Alpha,5Alpha)]- (9Ci) is a high-purity, stereochemically defined chiral building block essential for advanced organic synthesis. Its rigid bicyclic pinane skeleton and reactive acid chloride functionality make it a critical intermediate for constructing complex molecules with precise three-dimensional architecture. This compound is primarily sought after by pharmaceutical and agrochemical R&D teams for the development of novel active ingredients, where its defined stereochemistry is crucial for biological activity.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, where the pinane structure can contribute to unique biological properties.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Fragrance and Flavor Chemistry: The pinane core is a valuable starting material for synthesizing high-value aroma chemicals and terpenoid derivatives.
• Material Science Research: Employed in the creation of specialized polymers and advanced organic materials with tailored properties.
• Academic and R&D Laboratories: A valuable reagent for methodological studies in organic chemistry and total synthesis projects.

Basic Information

Product Name	Bicyclo[3.1.1]Heptane-2-Carbonyl Chloride, 6,6-Dimethyl-, [1S-(1Alpha,2Alpha,5Alpha)]- (9Ci)
CAS No.	150614-86-1
Molecular Formula	C10H15ClO
Molecular Weight	186.68 g/mol
Synonyms	(1S,2S,5S)-6,6-Dimethylbicyclo[3.1.1]heptane-2-carbonyl chloride; (-)-Myrtanoyl chloride; (1S,2S,5S)-(-)-Myrtanoyl chloride; (1S,2S,5S)-6,6-Dimethyl-2-bicyclo[3.1.1]heptanecarbonyl chloride; (1S,2S,5S)-Pinane-2-carbonyl chloride; (1S)-(-)-Myrtanoyl chloride; Pinan-2-carbonyl chloride, (-)-
EINECS	Contact for details

Quality Control

Every batch of our Bicyclo[3.1.1]Heptane-2-Carbonyl Chloride is manufactured and tested under strict quality management systems to ensure high chemical and chiral purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing specifications such as assay (by GC/HPLC), enantiomeric excess (by chiral HPLC), and impurity profiles. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable consistency and traceability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic and highly volatile nature, this material should be stored under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C for long-term stability. Allow the sealed container to reach ambient temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.