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1-(4-((1-(2-Amino-7-Methyl-4-Oxo-6-Pteridinyl)Ethyl)Amino)Phenyl)-1-Deoxy-(1-Ribofuranosyl)Ribitol CAS NO 150473-01-1


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CAS No.:150473-01-1

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

1-(4-((1-(2-Amino-7-Methyl-4-Oxo-6-Pteridinyl)Ethyl)Amino)Phenyl)-1-Deoxy-(1-Ribofuranosyl)Ribitol is a complex pteridine derivative with significant potential as a biochemical intermediate. This compound matters for its role in the research and development of novel therapeutic agents and enzyme inhibitors, particularly within the folate metabolic pathway. It is primarily needed by pharmaceutical R&D laboratories, biotechnology companies, and academic institutions focused on metabolic studies, oncology research, and the synthesis of specialized nucleotide analogs.

Application

  • Pharmaceutical Research & Development: Serves as a key intermediate or reference standard in the synthesis of novel folate antagonists and enzyme inhibitors.
  • Biochemical Studies: Used as a tool compound to investigate enzymatic pathways, particularly those involving dihydrofolate reductase (DHFR) and related enzymes.
  • Oncology Research: Investigated for its potential role in developing targeted cancer therapies that interfere with nucleotide synthesis in rapidly dividing cells.
  • Academic Research: Employed in universities and research institutes for metabolic pathway analysis and medicinal chemistry projects.
  • Reference Standard Manufacturing: Supplied to analytical and pharmaceutical companies for use as a high-purity certified reference material (CRM).
  • Precursor for Specialty Chemicals: Acts as a building block for the synthesis of more complex, functionally active pteridine-based molecules.

Basic Information

Product Name 1-(4-((1-(2-Amino-7-Methyl-4-Oxo-6-Pteridinyl)Ethyl)Amino)Phenyl)-1-Deoxy-(1-Ribofuranosyl)Ribitol
CAS No. 150473-01-1
Molecular Formula C₂₅H₃₃N₇O₈
Molecular Weight 559.58 g/mol
Synonyms 1-Deoxy-1-[4-[[1-(2-amino-7-methyl-4-oxo-6-pteridinyl)ethyl]amino]phenyl]-D-ribitol; 1-(4-((1-(2-Amino-7-methyl-4-oxo-3,4-dihydropteridin-6-yl)ethyl)amino)phenyl)-1-deoxy-D-ribitol; Pteridine ribitol derivative; Folate pathway intermediate; 6-[(1-{[4-(1-Deoxy-D-ribitol-1-yl)phenyl]amino}ethyl)-7-methyl-4-oxo-3,4-dihydropteridin-2-yl]amine; CAS 150473-01-1
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Quality Control

Our 1-(4-((1-(2-Amino-7-Methyl-4-Oxo-6-Pteridinyl)Ethyl)Amino)Phenyl)-1-Deoxy-(1-Ribofuranosyl)Ribitol is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment. We can supply material compliant with research-grade specifications and support custom purity requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a desiccated environment and away from direct light exposure to maintain stability and purity.

Specification

Item Specification
Appearance Off-white to light yellow powder
Identification (HPLC) Conforms to reference standard
Identification (IR) Conforms to structure
Assay (HPLC) ≥ 95.0%
Water Content (KF) ≤ 5.0%
Residue on Ignition ≤ 0.5%
Heavy Metals ≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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