Description

6-Oxocytidine is a modified nucleoside analog of cytidine, where the 6-position of the cytosine base is oxidized to a carbonyl group. This structural modification makes it a valuable intermediate and reference standard in the research and development of novel pharmaceuticals and biochemical tools. It is primarily utilized by research institutions and pharmaceutical companies engaged in nucleoside chemistry, antiviral drug discovery, and metabolic pathway studies. The compound's unique structure provides a critical building block for probing enzyme mechanisms and synthesizing targeted therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor in the development of novel antiviral and anticancer nucleoside analogs.
• Biochemical Research: Used as a reference standard and substrate in enzymatic studies, particularly for cytidine deaminase and other nucleoside-metabolizing enzymes.
• Proteomics & Metabolomics: Employed as a specialty reagent in mass spectrometry and chromatography for method development and compound identification.
• Antiviral Drug Discovery: Investigated for its potential role in the synthesis of mechanism-based inhibitors targeting viral replication.
• Academic Research: Utilized in university and institutional labs for fundamental studies in nucleic acid chemistry and modification.

Basic Information

Product Name	6-Oxocytidine
CAS No.	150439-90-0
Molecular Formula	C9H13N3O6
Molecular Weight	259.22 g/mol
Synonyms	6-Oxo-cytidine; 1-β-D-Ribofuranosyl-2-oxo-1,2-dihydropyrimidine-4-carboxamide; Cytidine, 6-oxo-; 4-Amino-1-β-D-ribofuranosyl-2(1H)-pyrimidinone; 6-Oxocytidine monohydrate (common hydrate form); 2-Oxo-4-amino-1-β-D-ribofuranosyl-1,2-dihydropyrimidine
EINECS	Contact for details

Quality Control

Our 6-Oxocytidine is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS). We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or development specifications. For custom synthesis or specific grade requirements (e.g., >98% HPLC purity), please contact our technical team.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed in a desiccated environment and away from direct light to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.