Description

2,5'-Anhydro-1-(2'-Deoxy-β-Erythro-Pentofuranosyl)-5-Guanidinylidene-2-Hydroxy-4-Oxoimidazolidine is a high-purity, specialized nucleoside analog with significant research and pharmaceutical development potential. This compound is valued for its unique structural features, which make it a critical intermediate in the synthesis of novel antiviral and anticancer agents. It is primarily sought by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers focused on nucleoside chemistry and drug discovery.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel antiviral and anticancer nucleoside analogs.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies related to DNA/RNA metabolism and repair.
• Medicinal Chemistry: Serves as a core scaffold for structure-activity relationship (SAR) studies to develop new therapeutic candidates.
• Reference Standard: Employed as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Process Development: Used in scaling up and optimizing synthetic routes for complex nucleoside-based active pharmaceutical ingredients (APIs).
• Academic Research: Fundamental studies in organic synthesis, carbohydrate chemistry, and heterocyclic compound behavior.

Basic Information

Product Name	2,5'-Anhydro-1-(2'-Deoxy-β-Erythro-Pentofuranosyl)-5-Guanidinylidene-2-Hydroxy-4-Oxoimidazolidine
CAS No.	150145-91-8
Molecular Formula	C11H15N5O5
Molecular Weight	297.27 g/mol
Synonyms	5-Guanidino-2,5'-anhydro-2'-deoxy-1-(β-D-erythro-pentofuranosyl)imidazolidin-4-one; 2,5'-Anhydro-1-(2-deoxy-β-D-erythro-pentofuranosyl)-5-(diaminomethylideneamino)-2-hydroxyimidazolidin-4-one; 5-Guanidinylidene-2,5'-anhydro-1-(2'-deoxy-β-D-erythro-pentofuranosyl)-2-hydroxy-4-oxoimidazolidine; 2,5'-Anhydro-1-(2-deoxy-β-D-ribofuranosyl)-5-guanidinylidene-2-hydroxy-4-oxoimidazolidine; NSC 677459; 5-(Diaminomethylideneamino)-2,5'-anhydro-1-(2-deoxy-β-D-erythro-pentofuranosyl)-2-hydroxyimidazolidin-4-one
EINECS	Contact for details

Quality Control

Our production of 2,5'-Anhydro-1-(2'-Deoxy-β-Erythro-Pentofuranosyl)-5-Guanidinylidene-2-Hydroxy-4-Oxoimidazolidine adheres to stringent quality protocols suitable for research and pharmaceutical development. Each batch is characterized and tested to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing comprehensive analytical results, including assay by HPLC and impurity profiles, are provided with every shipment. We support compliance with cGMP and ICH guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.