Description

5-(1-Azido-2-Chloroethyl)-2'-Deoxyuridine is a specialized nucleoside analog derivative, a key synthetic intermediate in advanced pharmaceutical and biochemical research. This compound is valued for its unique functional groups, which enable its use in the development of novel therapeutic agents and as a versatile building block in medicinal chemistry. It is primarily required by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers focused on antiviral drug discovery, prodrug synthesis, and the development of targeted molecular probes.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel antiviral and anticancer nucleoside analogs.
• Medicinal Chemistry Research: Serves as a versatile building block for structure-activity relationship (SAR) studies and prodrug development.
• Bioconjugation & Probe Synthesis: The azido group enables click chemistry applications for labeling, imaging, and targeted drug delivery systems.
• Biochemical Tool Development: Used in the creation of enzyme inhibitors and mechanism-based inactivators for biochemical studies.
• Academic & Industrial R&D: Fundamental research into modified nucleosides and their biological activities.
• Fine Chemical Synthesis: Employed in multi-step organic syntheses requiring protected and functionalized nucleoside scaffolds.

Basic Information

Product Name	5-(1-Azido-2-Chloroethyl)-2'-Deoxyuridine
CAS No.	150021-19-5
Molecular Formula	C11H13ClN6O5
Molecular Weight	344.71 g/mol
Synonyms	5-(1-Azido-2-chloroethyl)-2'-deoxyuridine; 2'-Deoxy-5-(1-azido-2-chloroethyl)uridine; 5-(2-Chloro-1-azidoethyl)-2'-deoxyuridine; 1-(2-Deoxy-β-D-erythro-pentofuranosyl)-5-(1-azido-2-chloroethyl)uracil; 150021-19-5; Azido-chloroethyl deoxyuridine; 5-Azidochloromethyldeoxyuridine derivative
EINECS	Contact for details

Quality Control

Our 5-(1-Azido-2-Chloroethyl)-2'-Deoxyuridine is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. We provide a Certificate of Analysis (COA) with every shipment, detailing all critical quality attributes to ensure it meets the stringent requirements of research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This material is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.