Description

Elisartan is a high-purity, non-peptide angiotensin II receptor antagonist (ARB) used as a key pharmaceutical intermediate. Its primary value lies in enabling the synthesis of advanced antihypertensive and cardiovascular APIs, offering a critical building block for modern drug development. This compound is essential for pharmaceutical manufacturers and R&D facilities focused on producing sartan-class medications for the global market.

Application

• Pharmaceutical Intermediate: Primary use in the synthesis of active pharmaceutical ingredients (APIs) for antihypertensive drugs.
• Angiotensin II Receptor Blocker (ARB) Development: Serves as a core scaffold for research and production of next-generation sartan medications.
• Cardiovascular Drug Research: Used in preclinical and clinical research for developing treatments for hypertension, heart failure, and diabetic nephropathy.
• Contract Manufacturing (CMO): Supplied to contract manufacturing organizations for large-scale API production under cGMP guidelines.
• Reference Standard: Can be utilized as a high-purity analytical reference standard for quality control and method validation.
• Academic & Institutional Research: Employed in biochemical and pharmacological studies investigating the renin-angiotensin system.

Basic Information

Product Name	Elisartan
CAS No.	149968-26-3
Molecular Formula	C24H25N5O3
Molecular Weight	431.49 g/mol
Synonyms	2-Butyl-1-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1H-benzimidazole-7-carboxylic acid; BIBR 277; BIBR-277; BIBR277; 1H-Benzimidazole-7-carboxylic acid, 2-butyl-1-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-; Telmisartan Impurity; Telmisartan Intermediate; BIBR 277 SE
EINECS	Contact for details

Quality Control

Our Elisartan is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for pharmaceutical synthesis. We provide comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles, with specifications aligned with ICH guidelines. Quality is assured through advanced analytical techniques including HPLC, GC, and NMR.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.