Description

2-Isothiocyanato-5-Methyl-10,11-Dihydro-5H-Dibenzo(A,D)Cyclohepten-5,10-Imine is a specialized organic building block featuring a fused dibenzocycloheptene core functionalized with an isothiocyanate group. This compound matters as a key synthetic intermediate for the development of novel pharmacologically active molecules, particularly in central nervous system (CNS) research. Pharmaceutical R&D laboratories and fine chemical manufacturers need this high-purity intermediate to synthesize and screen new chemical entities for therapeutic potential.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel tricyclic compounds with potential neurological activity.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies targeting CNS receptors.
• Bioconjugation & Probe Development: The reactive isothiocyanate group enables conjugation to amines, useful for creating fluorescent probes or affinity labels for biological targets.
• Academic & Institutional R&D: Employed in university and research institute laboratories for exploratory synthetic chemistry and drug discovery projects.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting outsourced drug discovery and custom synthesis programs.

Basic Information

Product Name	2-Isothiocyanato-5-Methyl-10,11-Dihydro-5H-Dibenzo(A,D)Cyclohepten-5,10-Imine
CAS No.	149715-73-1
Molecular Formula	C17H14N2S
Molecular Weight	278.37 g/mol
Synonyms	5H-Dibenzo[a,d]cyclohepten-5,10-imine, 10,11-dihydro-2-isothiocyanato-5-methyl-; 2-Isothiocyanato-5-methyl-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5,10-imine; 5-Methyl-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5,10-imine-2-yl isothiocyanate; NSC 339586; Dibenzo[a,d]cycloheptenimine isothiocyanate derivative
EINECS	Contact for details

Quality Control

Our 2-Isothiocyanato-5-Methyl-10,11-Dihydro-5H-Dibenzo(A,D)Cyclohepten-5,10-Imine is produced under strict quality management systems to ensure batch-to-batch consistency and high purity for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We support compliance with relevant guidelines for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep the container sealed to protect from moisture. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.