Description

5'-o-Methyl-Dt Cep CAS NO 149681-62-9 is a high-purity, chemically modified nucleoside derivative used as a critical building block in advanced pharmaceutical synthesis and oligonucleotide research. This compound is essential for the development of novel therapeutic agents, particularly in the fields of antiviral and anticancer drug discovery. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in the production of nucleoside analogs and modified oligonucleotides.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor for the development of novel antiviral and anticancer nucleoside analogs.
• Oligonucleotide Synthesis: Used in the solid-phase synthesis of modified DNA/RNA strands for research and therapeutic applications.
• Biochemical Research: Acts as a substrate or inhibitor in enzymatic studies to understand nucleic acid metabolism and related pathways.
• Prodrug Development: Employed in the design of prodrugs to enhance the bioavailability and targeting of nucleoside-based therapeutics.
• Antisense Technology: Incorporated into antisense oligonucleotides to improve their stability, binding affinity, and pharmacokinetic properties.
• Diagnostic Probe Synthesis: Utilized in creating labeled probes for genetic testing and molecular diagnostics.

Basic Information

Product Name	5'-o-Methyl-Dt Cep
CAS No.	149681-62-9
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	5'-O-Methyl-2'-deoxythymidine 3'-(2-cyanoethyl N,N-diisopropylphosphoramidite); 5'-O-Methyl-dT-CE Phosphoramidite; 5'-O-Methylthymidine 3'-CE Phosphoramidite; dT(5'-OMe) Phosphoramidite; 5'-Methyl-dT-CEP; 5'-O-Methyl-2'-deoxythymidine 3'-(β-cyanoethyl) phosphoramidite; 5'-O-Methyl-dT phosphoramidite
EINECS	Contact for details

Quality Control

Our 5'-o-Methyl-Dt Cep is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, suitable for sensitive pharmaceutical R&D applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles as determined by advanced analytical techniques including HPLC and NMR. We adhere to cGMP principles where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and performance. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen.

Specification

Item	Specification
Appearance	White to off-white solid or foam
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 2.0%
Solubility	Soluble in anhydrous acetonitrile, DMF

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.