Description

β-D-Arabinofuranosylamine, 2-Deoxy-2-Fluoro- (9Ci) is a fluorinated nucleoside analog, a key building block in medicinal chemistry and pharmaceutical research. This compound matters for its role as a critical intermediate in the synthesis of novel antiviral and anticancer agents, particularly those targeting viral polymerases. Pharmaceutical R&D laboratories and fine chemical manufacturers need it to develop next-generation therapeutics, leveraging its modified sugar moiety to enhance drug stability and biological activity.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of fluorinated nucleoside analogs for antiviral and anticancer drug discovery.
• Antiviral Agent Research: Used in the development of potential therapeutics against viruses such as hepatitis B (HBV) and hepatitis C (HCV).
• Oncology Research: Serves as a building block for creating nucleoside-based chemotherapeutic agents that inhibit DNA/RNA synthesis in cancer cells.
• Biochemical Probe: Utilized in enzymatic studies to investigate the mechanism of action of polymerases and nucleoside-metabolizing enzymes.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to optimize the pharmacokinetic and pharmacodynamic properties of lead compounds.
• Process Chemistry & Scale-up: Serves as a validated intermediate for the GMP-compliant manufacturing of active pharmaceutical ingredients (APIs).

Basic Information

Product Name	β-D-Arabinofuranosylamine, 2-Deoxy-2-Fluoro- (9Ci)
CAS No.	149624-26-0
Molecular Formula	C9H13FN2O4
Molecular Weight	232.21 g/mol
Synonyms	2'-Deoxy-2'-fluoro-β-D-arabinofuranosylamine; 2-Fluoro-2-deoxy-β-D-arabinofuranosylamine; 2'-F-β-D-Arabinofuranosylamine; 2'-Fluoro-2'-deoxy-β-D-arabinofuranosylamine; 1-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)amine; β-2'-F-Arabinosylamine; 2-Fluoroarabinofuranosylamine; 149624-26-0
EINECS	Contact for details

Quality Control

Our β-D-Arabinofuranosylamine, 2-Deoxy-2-Fluoro- (9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and MS, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) with full traceability are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed in a desiccated environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.