Description

2H-Indazole-3-Carbonylchloride,4,5,6,7-Tetrahydro-2-Methyl-(9Ci) is a versatile and reactive chemical intermediate, specifically an acid chloride derivative of a tetrahydroindazole. This compound is valued for its role as a key building block in sophisticated organic synthesis, enabling the efficient introduction of the indazole pharmacophore. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients. Its reactive carbonyl chloride group makes it an essential precursor for amide bond formation and other coupling reactions.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides with enhanced efficacy.
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Peptide Mimetic Development: Employed to create indazole-based peptidomimetics for modulating protein-protein interactions.
• Material Science Precursor: Potential use in synthesizing specialized polymers or ligands for catalytic systems.

Basic Information

Product Name	2H-Indazole-3-Carbonylchloride,4,5,6,7-Tetrahydro-2-Methyl-(9Ci)
CAS No.	149591-34-4
Molecular Formula	C9H11ClN2O
Molecular Weight	198.65 g/mol
Synonyms	4,5,6,7-Tetrahydro-2-methyl-2H-indazole-3-carbonyl chloride; 2-Methyl-4,5,6,7-tetrahydro-2H-indazole-3-carbonyl chloride; 2-Methyl-4,5,6,7-tetrahydroindazole-3-carboxylic acid chloride; 1-Methyl-4,5,6,7-tetrahydro-1H-indazole-3-carbonyl chloride (tautomer); 149591-34-4; Tetrahydro-2-methyl-2H-indazole-3-carbonyl chloride
EINECS	Contact for details

Quality Control

Every batch of 2H-Indazole-3-Carbonylchloride,4,5,6,7-Tetrahydro-2-Methyl-(9Ci) is manufactured and tested under a strict quality management system. We ensure high purity and consistency to meet the exacting standards of advanced synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment. Our quality protocols are designed to support cGMP (current Good Manufacturing Practice) requirements for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Recommended long-term storage temperature is 2-8°C (refrigerated).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.